John H Krystal Selected Research

Anesthetics (Anesthetic Agents)

1/2022

Validation of ketamine as a pharmacological model of thalamic dysconnectivity across the illness course of schizophrenia.

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John H Krystal Research Topics

Disease

55	Schizophrenia (Dementia Praecox) 01/2022 - 06/2002
48	Alcoholism (Alcohol Abuse) 01/2022 - 07/2002
45	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 07/2022 - 05/2008
21	Psychotic Disorders (Schizoaffective Disorder) 02/2022 - 04/2002
13	Mental Disorders (Mental Disorder) 06/2022 - 04/2004
11	Wounds and Injuries (Trauma) 01/2022 - 09/2011
10	Treatment-Resistant Depressive Disorder 06/2022 - 03/2003
9	Substance-Related Disorders (Drug Abuse) 01/2021 - 05/2004
9	Mood Disorders (Mood Disorder) 01/2019 - 11/2003
8	Cognitive Dysfunction 06/2022 - 05/2004
8	Major Depressive Disorder (Major Depressive Disorders) 01/2022 - 05/2003
7	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 12/2012 - 05/2003
6	Bipolar Disorder (Manic Depressive Psychosis) 01/2021 - 04/2006
6	Panic Disorder (Panic Attack) 11/2019 - 03/2004
6	Anxiety Disorders (Anxiety Disorder) 10/2016 - 12/2004
5	Hallucinations (Hallucination) 01/2022 - 01/2003
3	Syndrome (Syndromes) 01/2022 - 04/2017
3	Substance Withdrawal Syndrome (Withdrawal Symptoms) 04/2007 - 09/2006
2	Pain (Aches) 02/2022 - 01/2020
2	Obesity 01/2022 - 01/2021
2	Sleepiness 01/2020 - 08/2011
2	Tobacco Use Disorder (Nicotine Dependence) 10/2018 - 09/2011
2	Treatment-Resistant Schizophrenia 01/2018 - 06/2009
2	Opioid-Related Disorders (Opiate Addiction) 09/2014 - 04/2002
2	Drug Resistant Epilepsy 08/2008 - 03/2002
2	Epilepsy (Aura) 08/2008 - 02/2005
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2008 - 01/2006
1	Lower Urinary Tract Symptoms 06/2022
1	Dysuria 06/2022
1	Sleep Initiation and Maintenance Disorders (Insomnia) 10/2021

Drug/Important Bio-Agent (IBA)

42	Ketamine FDA LinkGeneric 07/2022 - 11/2003
30	Glutamic Acid (Glutamate)FDA Link 01/2022 - 07/2003
25	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 07/2002
21	Antidepressive Agents (Antidepressants)IBA 07/2022 - 03/2007
20	N-Methylaspartate (NMDA)IBA 01/2017 - 07/2003
16	Pharmaceutical PreparationsIBA 01/2021 - 03/2004
16	gamma-Aminobutyric Acid (GABA)IBA 01/2021 - 09/2002
14	Antipsychotic Agents (Antipsychotics)IBA 01/2020 - 06/2002
11	Glutamate Receptors (Glutamate Receptor)IBA 01/2017 - 07/2003
9	Naltrexone (ReVia)FDA LinkGeneric 01/2019 - 03/2004
9	Risperidone (Risperdal Consta)FDA LinkGeneric 12/2017 - 03/2011
8	Ethanol (Ethyl Alcohol)IBA 10/2013 - 07/2003
8	Riluzole FDA LinkGeneric 01/2008 - 05/2003
7	Biological ProductsIBA 01/2022 - 10/2010
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2005
7	Nicotine FDA Link 01/2014 - 04/2004
6	Serotonin (5 Hydroxytryptamine)IBA 01/2020 - 07/2002
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2011
5	Dopamine (Intropin)FDA LinkGeneric 02/2020 - 09/2005
5	Cycloserine (Seromycin)FDA Link 11/2019 - 02/2010
4	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2018 - 12/2006
4	Excitatory Amino Acid AntagonistsIBA 01/2017 - 10/2004
4	Amino Acids FDA Link 01/2008 - 11/2003
3	Therapeutic UsesIBA 02/2022 - 01/2019
3	EnzymesIBA 10/2021 - 12/2004
3	BenzodiazepinesIBA 11/2019 - 12/2004
3	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 11/2019 - 01/2006
3	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2018 - 05/2008
3	Memantine (Namenda)FDA Link 02/2015 - 04/2006
3	Neurotransmitter Agents (Neurotransmitter)IBA 05/2013 - 11/2003
3	Protons (Proton)IBA 08/2006 - 09/2002
2	EsketamineIBA 06/2022 - 12/2017
2	CannabinoidsIBA 02/2022 - 01/2011
2	saracatinibIBA 01/2022 - 01/2021
2	Phosphotransferases (Kinase)IBA 01/2022 - 01/2022
2	Hydrocortisone (Cortisol)FDA LinkGeneric 10/2021 - 04/2002
2	GlucocorticoidsIBA 10/2021 - 01/2017
2	N-Methyl-3,4-methylenedioxyamphetamine (MDMA)IBA 01/2021 - 05/2004
2	Metabotropic Glutamate 5 ReceptorIBA 11/2020 - 01/2017
2	metabotropic glutamate receptor 2IBA 10/2020 - 08/2010
2	Apolipoproteins E (ApoE)IBA 01/2019 - 01/2018
2	ApolipoproteinsIBA 01/2019 - 01/2018
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 12/2017
2	Haloperidol (Haldol)FDA LinkGeneric 01/2014 - 06/2009
2	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 12/2011 - 06/2007
2	Clozapine (Clozaril)FDA LinkGeneric 06/2009 - 07/2005
2	Glutamine (L-Glutamine)FDA Link 08/2008 - 02/2005
2	Excitatory Amino Acid AgentsIBA 05/2008 - 07/2003
2	Disulfiram (Antabuse)FDA Link 01/2008 - 03/2004
2	Butyric Acid (Butanoic Acid)IBA 03/2007 - 04/2005
2	GABA-A Receptors (GABA(A) Receptor)IBA 09/2006 - 08/2005
2	NeurosteroidsIBA 08/2006 - 09/2002
2	salicylhydroxamic acid (SHAM)IBA 07/2005 - 01/2003
1	erucylphosphocholineIBA 01/2022
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2022
1	tau Proteins (tau Protein)IBA 01/2022
1	Hormones (Hormone)IBA 01/2022
1	Anesthetics (Anesthetic Agents)IBA 01/2022
1	CreatinineIBA 01/2022
1	FurinIBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 10/2021
1	AS2471907IBA 10/2021
1	phosphatidylethanolIBA 01/2021
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2021
1	Sertraline (Zoloft)FDA LinkGeneric 01/2021
1	NeuropeptidesIBA 01/2021

Therapy/Procedure

28	Drug Therapy (Chemotherapy) 10/2021 - 09/2003
14	Therapeutics 06/2022 - 09/2005
3	Injections 01/2014 - 03/2011
3	Transcranial Magnetic Stimulation 11/2007 - 01/2003